Janos Kirz


Research Professor
Department of Physics and Astronomy
Stony Brook University
Stony Brook, NY 11794-3800
 
Email: janos.kirz@sunysb.edu

 


Scientific Advisor
Advanced Light Source
Lawrence Berkeley National Laboratory
MS 80R0114
Berkeley, CA 94720-8229

Tel: 510-486-5423
Fax: 510-486-4960
Email: jkirz@lbl.gov



 

Curricula Vitae: http://xray1.physics.sunysb.edu/~kirz/cv.pdf

Home page: http://xray1.physics.sunysb.edu/

Publications: http://xray1.physics.sunysb.edu/~kirz/publications.pdf

 

Research Interests

Soft x-ray microscopy and diffraction based imaging of biological specimens.  I collaborate with Prof. Chris Jacobsen, using beamline 9.0.1 at the Advanced Light Source. We developed a scanning transmission x-ray microscope using zone plate focusing. The resolution is intermediate between that of light and electron microscopes. The specimen may be wet, and up to 10 microns thick. Using absorption spectroscopy, information about the microchemical environment may be obtained.

On diffraction based imaging Prof. Jacobsen and I collaborate with Dr. David Sayre, originator of the idea. Our experimental program started at the National Synchrotron Light Source, but is at the Advanced Light Source in Berkeley since the fall of 2003.

Some Recent Publications

D. Shapiro, P. Thibault, T. Beetz, V. Elser, M. Howells, C. Jacobsen, J. Kirz, E. Lima, H. Miao, A. N. Neiman and D. Sayre, "Biological imaging by soft x-ray diffraction microscopy", PNAS 102, 15343-15346 (2005)

J. Miao, H. N. Chapman, J. Kirz, D. Sayre, and K. O. Hodgson, "Taking X-ray Diffraction to the Limit: Macromolecular Structures from Femtosecond X-Ray Pulses and Diffraction Microscopy of Cells with Synchrotron Radiation," Ann. Rev. Biophys. Biomolec. Struct. 33, 157-176 (2004).

T. Beetz, M. Feser, H. Fleckenstein, B. Hornberger, C. Jacobsen, J. Kirz, M. Lerotic, E. Lima, M. Lu, D. Sayre, D. Shapiro, A. Stein, D. Tennant, and S. Wirick, "Soft x-ray microscopy at the NSLS," Synchrotron Radiation News 16, no. 3, pp. 11-15, (2003).

T. Beetz, C. Jacobsen, C.-C. Kao, J. Kirz, O. Mentes, C. Sanchez-Hanke, D. Sayre, and D. Shapiro, "Development of a novel apparatus for experiments in soft x-ray diffraction imaging and diffraction tomography," Journal de Physique IV 104, pp. 27-30, (2003).

B. Winn, H. Ade, C. Buckley, M. Feser, M. Howells, S. Hulbert, C. Jacobsen, K. Kaznacheyev, J. Kirz, A. Osanna, J. Maser, I. McNulty, J. Miao, T. Oversluizen, S. Spector, B. Sullivan, S. Wang, S. Wirick, and H. Zhang, "Illumination for coherent soft x-ray applications: The new X1A beamline at the NSLS," Journal of Synchrotron Radiation 7,  395-404, (2000).

J. Maser, A. Osanna, Y. Wang, C. Jacobsen, J. Kirz, S. Spector and B. Winn, "Soft x-ray microscopy with a cryo STXM: I. Instrumentation, imaging, and spectroscopy,'' J. Microscopy 197, 68-79 (2000).

J. Miao, P. Charalambous, J. Kirz and D. Sayre, "An extension of the methods of x-ray crystallography to allow imaging of micron-size non-crystalline specimens,'' Nature 400, 342-344 (1999).

C. Jacobsen and J. Kirz, "X-ray microscopy with synchrotron radiation," Nature Structural Biology 5 (supplement), 650-653 (1998).